The Foundations of Longevity: Why Living Longer Is Not the Same as Living Well

Dr. John Sciales

Published on: 31/01/2026

A systems-based manifesto on longevity that explains why healthspan fails before lifespan, and how metabolism, insulin resistance, inflammation, and biology determine whether aging is marked by strength or decline.

LongevityHealthwellnessmetabolismheartdiabetesinsulin resistancemetforminhealthspan

Why Metformin-Centered Therapy Is Failing Heart Patients — and What Really Restores Metabolic Health

Dr. John Sciales

Published on: 20/01/2026

Blood sugar is not the disease. Learn why metformin-centered care often fails to restore energy or protect the heart, and how insulin resistance, inflammation, and mitochondrial health drive true cardiometabolic recovery.

metformininsulin resistancesugardiabetesheart diseasemetabolismcardiometabolicglucose centric medicineholistic